This book, ‘Medicinal Chemistry’ has two objectives in view. The first objective is to attract the interest of the undergraduate students in developing countries, so that they feel a spontaneous urge to explore and understand the basic theories of medicinal chemistry. These students often encounter enormous difficulties in grasping the fundamentals of synthesis of simple as well as complex compounds including those belonging to the therapeutic group, and they often get confused when they are supplied with inadequate information of vitally important medicinal compounds, their chemical formula and chemical names. So this book aims at removing this inadequacy by furnishing copious information about medicinal compounds and pointing out their inter-relations wherever they exist. This method, it is believed, will add new incentive to the study of the subject, and will boost the spirit of research and provide a new dimension to the study of medicinal chemistry. Thus, in this book an attempt has been made to include and correlate detailed accounts of most of the important categories of drugs usually taught in the various Universities of developing countries offering diploma, degree and honours courses in Pharmacy. The second objective that has been kept in view is to make this a handy reference book for the professional class. With a view to fulfilling this second objective the author has adopted a specific style.
Each chapter has been sub-divided into three sections in the following manner. First, a brief introduction. Second, it follows classification based on either chemical or pharmacological basis. Each category of compound also includes the important representative members of the respective groups together with their International Non-proprietory Names (INN), British Approved Names (BAN) and United States Approved Names (USAN) wherever applicable. Then comes the statement of its chemical name(s), official status in B.P., U.S.P., Eur. P., Int. P., Ind. P., and their proprietory name(s). The third part, perhaps the most significant, contains the synthesis of various important members treated individually, brief description of the synthesis, therapeutic applications of each compound, together with its dosage in various diseases, and routes of administration. The dosage for adults and children have been separately mentioned. The usual and maintenance doses, wherever applicable, have also been specified. The mode of action of various classes of medicinal compounds in addition to the structure-activity relationship (SAR) have also been elaborated wherever relevant. Greater emphasis has been laid on the chemistry of various compounds treated in this book, so that an undergraduate student may acquire a comprehensive knowledge on the basic concepts of the medicinal chemistry. For the reasons mentioned above, it is believed that this book will enjoy equal favour and confidence with pharmacy students, practising pharmacists and also with medical service representatives. Manufacturing pharmacists engaged in basic drug manufacture may also find it a useful reference book, and will appreciate its originality of approach and its significant departure from similar books available on the subject.
0 comments:
Post a Comment