Over the past
decade, nanotechnology has been a buzzword that the scientific community has
embraced with great compassion. The emergence of nanotechnology has had a
profound effect on almost every aspect of the twenty-first century’s daily
life. It has had a revolutionary impact from stain-resistant clothing and
cosmetics to environmental issues, including energy and medicine and even
aerospace engineering. This volume, comprised of nine Reviews, nine new
Protocols, and one Future Directions chapter, is an endeavor to present various
aspects of nanotechnology from the oxidative stress point of view. The authors
reflect the large participation of internationally eminent researchers, who have
already distinguished themselves by making a deep impact in the fields of
nanotechnology and oxidative stress. Starting from a single concept,
nanotechnology has emerged as one of the fastest growing niches in this
exciting field. Proponents of this avant-garde technology also describe it as
one of the most prevalent engineering innovations in science and society since
the Industrial Revolution.
There is an
enormous disparity between the amount of funding dedicated to nanoparticle safety
studies as compared to its mammoth applications in industrial and consumer products.
However, there has been a sustaining interest by the scientific community in
the effects of short-term and chronic exposure to nanomaterials on humans and
the environment. Succinct nanoparticles are defined as submicron particles,
usually <100 nm in size. Materials in this range usually produce a set of
distinctive physicochemical properties. Therefore, size, chemical composition,
and surface properties of nanomaterials play a crucial role in oxidative
stress-induced nanotoxicity. Part I of this volume includes detailed Reviews
and characterization of different types of nanomaterials, including polymeric
and inorganic nanoparticles, nanotubes, nanogels, and quantum dots along with
their adverse effects, particularly nanotoxicity induced by oxidative stress.
It also reviews in vivo and in vitro toxic effects caused by oxidative stress
as a result of exposure to nanomaterials.
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