The beginning of interphase cytogenetics can be
attributed to significant advances in human molecular genetics and
cytogenetics. Owing to experimental and theoretical research at the
interface between cellular and molecular levels of chromosomal organization and
function, high-resolution techniques for chromosomal analysis (molecular
cytogenetic techniques) have become available. Molecular cytogenetics is a
branch of biomedical sciences that explores chromosomes at molecular and
single-cell resolutions at all stages of the cell cycle. It also comprises the
techniques that operate with either the entire genome or specific DNA sequences
to analyze genomic structural and functional variations at chromosomal level.
In postgenomic era, molecular cytogenetics has appreciably transformed and has
given rise to a new field of genomics, called cytogenomics. As a result, new
opportunities have emerged for analysis of human interphase chromosomes in
almost all cell types and states at unprecedented resolution. In Human Interphase Chromosomes, the
editors have provided an overview of current developments in the study of human
interphase chromosomes with a special attention to available molecular
cytogenetictechnologies for basic and clinical chromosome research.
0 comments:
Post a Comment