MicroRNAs (miRNAs) are RNA molecules, conserved by evolution,
that regulate gene expressions and their recent discovery is revolutionising
both basic biomedical research and drug discovery. Expression levels of MiRNAs
have been found to vary between tissues and with developmental stages and hence
evaluation of the global expression of miRNAs potentially provides
opportunities to identify regulatory points for many different biological
processes. This wide-ranging reference work, written by leading experts from
both academia and industry, will be an invaluable resource for all those
wishing to use miRNA techniques in their own research, from graduate students,
post-docs and researchers in academia to those working in R&D in biotechnology
and pharmaceutical companies who need to understand this emerging technology.
From the discovery of miRNAs and their functions to their detection and role in
disease biology, this volume uniquely integrates the basic science with
industry application towards drug validation, diagnostic and therapeutic
development.
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